Immunologic Factor
omalizumab
Brand Names:
Xolair
Effect:
Decreased IgE Activity
May Treat:
Asthma
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to omalizumab:
  • A humanized monoclonal antibody directed against the C-epsilon 3 domain of immunoglobulin E. Olizumab binds to this IgE domain, thereby preventing IgE from binding to its high-affinity mast-cell receptor. (NCI04)
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • An anti-IgE, recombinant, humanized monoclonal antibody which specifically binds to the C epsilon3 domain of IMMUNOGLOBULIN E, the site of high-affinity IgE receptor binding. It inhibits the binding of IgE to MAST CELLS and BASOPHILS to reduce the severity of the allergic response and is used in the management of persistent allergic ASTHMA.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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