Immunologic Factor
bevacizumab Audio
[ beh-vuh-sih-zoo-mab ]
Brand Names:
Avastin; Mvasi; Zirabev
Effect:
Vascular Growth Decrease
May Treat:
Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Fallopian Tube Neoplasms; Glioblastoma; Kidney Neoplasms; Ovarian Neoplasms; Peritoneal Neoplasms; Uterine Cervical Neoplasms
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to bevacizumab:
  • A drug used to treat several types of cancer, including certain types of colorectal, lung, breast, and kidney cancers and glioblastoma. It is also being studied in the treatment of other types of cancer. Avastin binds to vascular endothelial growth factor (VEGF) and may prevent the growth of new blood vessels that tumors need to grow. It is a type of antiangiogenesis agent and a type of monoclonal antibody.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A recombinant humanized monoclonal antibody directed against the vascular endothelial growth factor (VEGF), a pro-angiogenic cytokine. Bevacizumab binds to VEGF and inhibits VEGF receptor binding, thereby preventing the growth and maintenance of tumor blood vessels.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • An anti-VEGF humanized murine monoclonal antibody. It inhibits VEGF RECEPTORS and helps to prevent PATHOLOGIC ANGIOGENESIS.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.