Disease or Syndrome
palmoplantar hyperkeratosis
Definitions related to palmoplantar keratosis:
  • (palmoplantar hyperkeratosis) Abnormal thickening of the skin localized to the palm of the hand and the sole of the foot.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2025
  • Palmoplantar keratoderma (PPK) constitutes a heterogeneous group of disorders characterized by thickening of the palms and the soles of individuals who are affected. In recent years, speculation has arisen that a molecular genetic classification system will replace the traditional, clinically based, descriptive systems.
    Medscape
    WebMD, 2025
  • Palmoplantar keratoderma (PPK) is a group of skin conditions characterized by thickening of the skin on the palms of the hands and soles of the feet. PPK can also be a feature of various underlying syndromes. In rare forms of PPK, organs other than the skin may also be affected. PPK can be either acquired during the lifetime (more...
    NIH Genetic and Rare Diseases
    National Center for Advancing Translational Sciences
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