• (penile induration) A condition characterized by hardening of the PENIS due to the formation of fibrous plaques on the dorsolateral aspect of the PENIS, usually involving the membrane (tunica albuginea) surrounding the erectile tissue (corpus cavernosum penis). This may eventually cause a painful deformity of the shaft or constriction of the urethra, or both.
  NLM Medical Subject Headings
  U.S. National Library of Medicine, 2025
• (peyronie's disease) Scarring of some of the tissue inside the penis, causing the penis to bend at an angle during an erection.
  Harvard Dictionary of Health Terms
  Harvard Medical Publishing, 2011
• (penile fibromatosis) Fibromatosis arising from the soft tissues of the penis. It is characterized by the presence of spindle-shaped fibroblasts, and an infiltrative growth pattern. It causes the penis to bend when it becomes erect.
  NCI
  U.S. National Cancer Institute, 2021
• Peyronie disease is fibrosis of the cavernous sheaths leading to contracture of the investing fascia of the corpora, resulting in a deviated and sometimes painful erection.
  Merck Manuals
  Merck & Co., Inc., 2025
• Fran�ois Gigot de Peyronie is widely credited for first describing penile curvature, now known as Peyronie disease (PD), in 1743. However, the precise etiology of this condition remains unclear.
  Medscape
  WebMD, 2025
• Peyronie's (pay-roe-NEEZ) disease is a noncancerous condition resulting from fibrous scar tissue that develops on the penis and causes curved, painful erections. Penises vary in shape and size, and having a curved erection isn't necessarily a cause for concern. But Peyronie's disease causes a significant bend or pain in some men.
  Mayo Clinic
  Mayo Foundation for Medical Education and Research, 2025