Pharmacologic Substance
pipobroman
Effect:
Decreased DNA Integrity; Decreased DNA Replication; Decreased Transcription to RNA
May Treat:
Leukemia;
Polycythemia Vera
Definitions related to pipobroman:
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A piperazine derivative with potential antineoplastic alkyating activity. Although the exact mechanism of action of pipobroman has yet to be fully elucidated, this agent appears to act by alkylating DNA, leading to disruption of DNA replication and eventually cell death.NCI ThesaurusU.S. National Cancer Institute, 2021
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An antineoplastic agent that acts by alkylation.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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