Pharmacologic Substance
trazodone Audio
[ trey-zuh-dohn ]
Brand Names:
Oleptro
Effect:
Increased Central Nervous System Serotonin Activity
May Treat:
Depressive Disorder; Sleep Initiation and Maintenance Disorders
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to trazodone:
  • A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A synthetic triazolopyridine derivative, antidepressant and sedative Trazodone acts as a serotonin uptake inhibitor, chemically unrelated to tricyclic, tetracyclic, or other antidepressants. It is effective in patients with schizoaffective disorders; major depressive disorders; and depressive disorders associated with insomnia and anxiety. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.