Cell Component
podosome
Subclass of:
Cell Surface Extensions;
Endothelial Cells
Definitions related to podosomes:
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An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm.Gene Ontology DictionaryGene Ontology Consortium, 2021
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Actin-rich adhesive structures found at the ventral surface of metazoan ENDOTHELIAL CELLS. When found in cultured cancer cells they are referred to as invadopodia. These are matrix-degrading structures composed of an ACTIN CYTOSKELETON core and an INTEGRINS-containing ring complex.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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