Pharmacologic Substance
pyrazinamide
[ pir-uh-zin-uh-mahyd, -mid ]
Brand Names:
Rifater
Effect:
Unknown Physiological Effect
May Prevent:
Tuberculosis
May Treat:
Tuberculosis
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to pyrazinamide:
  • A pyrazine that is used therapeutically as an antitubercular agent.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A synthetic pyrazinoic acid amide derivative with bactericidal property. Pyrazinamide is particularly active against slowly multiplying intracellular bacilli (unaffected by other drugs) by an unknown mechanism of action. Its bactericidal action is dependent upon the presence of bacterial pyrazinamidase, which removes the amide group to produce active pyrazinoic acid. Pyrazinamide is an important component of multidrug therapy for tuberculosis. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
  • Antibacterial derived from nicotinic acid, used as a tuberculostatic.
    CRISP Thesaurus
    National Institutes of Health, 2006
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.