Pharmacologic Substance
sitagliptin phosphate
Effect:
Decreased Glucagon Secretion; Increased Insulin Secretion
May Treat:
Diabetes Mellitus, Type 2
More Information:
Definitions related to sitagliptin phosphate:
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A pyrazine-derived DIPEPTIDYL-PEPTIDASE IV INHIBITOR and HYPOGLYCEMIC AGENT that increases the levels of the INCRETIN hormones GLUCAGON-LIKE PEPTIDE-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). It is used in the treatment of TYPE 2 DIABETES.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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The phosphate salt form of sitagliptin, an orally available, competitive, beta-amino acid-derived inhibitor of dipeptidyl peptidase 4 (DDP-4) with hypoglycemic activity. Sitagliptin may cause an increased risk in the development of pancreatitis.NCI ThesaurusU.S. National Cancer Institute, 2021
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