Pathologic Function
rhabdomyolysis
rhab·do·my·ol·y·sis
Subclass of:
Myopathy
Definitions related to rhabdomyolysis:
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A clinical syndrome resulting from direct or indirect muscle injury and subsequent release of myoglobin into the plasma.NCI ThesaurusU.S. National Cancer Institute, 2021
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Breakdown of muscle fibers that leads to the release of muscle fiber contents (myoglobin) into the bloodstream.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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Necrosis or disintegration of skeletal muscle often followed by myoglobinuria.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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A disorder characterized by the breakdown of muscle tissue resulting in the release of muscle fiber contents into the bloodstream.Common Terminology Criteria for Adverse EventsU.S. National Institutes of Health, 2021
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Rhabdomyolysis is a clinical syndrome involving the breakdown of skeletal muscle tissue. Symptoms and signs include muscle weakness, myalgias, and reddish-brown urine, although this triad is present in less than 10% of patients. Diagnosis of rhabdomyolysis is by history and laboratory confirmation of elevated creatine kinase (CK) of...Merck & Co., Inc., 2020
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Rhabdomyolysis (literally, �dissolution of skeletal muscle�) is a syndrome caused by injury to skeletal muscle and involves leakage of large quantities of potentially toxic intracellular contents into plasma. First described in the victims of crush injury during World War II, it is a final pathway of diverse processes and insults.WebMD, 2019
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Rhabdomyolysis may result from any traumatic or medical injury to the sarcolemma (the myocyte cell membrane). The subsequent release of intracellular ions, myoglobin, CK, and urates into the circulation results in electrolyte disturbances, disseminated intravascular coagulation (DIC), renal failure, and multiorgan failure. The...Athenahealth, Inc., 2019
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