Antibiotic
spectinomycin Audio
spec·ti·no·my·cin [ spek-tuh-noh-mahy-sin ]
Brand Names:
SpectoGard
Effect:
Decreased Protein Synthesis
May Prevent:
Mycoplasma Infections
May Treat:
Escherichia coli Infections; Gonorrhea
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to spectinomycin:
  • An aminocyclitol aminoglycoside antibiotic derived from Streptomyces spectabilis with bacteriostatic activity. Spectinomycin binds to the bacterial 30S ribosomal subunit. As a result, this agent interferes with the initiation of protein synthesis and with proper protein elongation. This eventually leads to bacterial cell death.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • An antibiotic produced by Streptomyces spectabilis. It is active against gram-negative bacteria and used for the treatment of GONORRHEA.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • Spectinomycin is a bacteriostatic antibiotic chemically related to the aminoglycosides. Spectinomycin binds to the 30S subunit of the ribosome, thus inhibiting bacterial protein synthesis. Its activity is restricted to gonococci. Spectinomycin is excreted by glomerular filtration.
    Merck Manuals
    Merck & Co., Inc., 2020
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