Antibiotic
puromycin Audio
pu·ro·my·cin
Subclass of:
Aminoglycosides; Cinnamates; Adenosine
Definitions related to puromycin:
  • A cinnamamido ADENOSINE found in STREPTOMYCES alboniger. It inhibits protein synthesis by binding to RNA. It is an antineoplastic and antitrypanosomal agent and is used in research as an inhibitor of protein synthesis.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • An aminoglycoside antibiotic isolated from the bacterium Streptomyces alboniger. Acting as an analog of the 3' terminal end of aminoacyl-tRNA, puromycin incorporates itself into a growing polypeptide chain and causes its premature termination, thereby inhibiting protein synthesis. This agent has antimicrobial, antitrypanosomal, and antineoplastic properties; it is used as an antibiotic in cell culture. (NCI04)
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Antibiotic produced by Streptomyces alboniger, used as an antineoplastic and antitrypanosomal agent and in research as an inhibitor of protein synthesis.
    CRISP Thesaurus
    National Institutes of Health, 2006
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