Biologically Active Substance
tetrodotoxin
te·tro·do·tox·in [ te-troh-duh-tok-sin ]
Subclass of:
Marine Toxins;
Quinazolines
Definitions related to tetrodotoxin:
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A neurotoxin with potential analgesic activity. Tetrodotoxin binds to the pores of fast voltage-gated fast sodium channels in nerve cell membranes, inhibiting nerve action potentials and blocking nerve transmission. Although found in various species of fish (such as the pufferfish), newts, frogs, flatworms, and crabs, tetrodotoxin, for which there is no known antidote, is actually produced by bacteria such as Vibrio alginolyticus, Pseudoalteromonas tetraodonis, and other vibrio and pseudomonas bacterial species.NCI ThesaurusU.S. National Cancer Institute, 2021
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Aminoperhydroquinazoline poison found mainly in species of puffer fishes, and some newts; the toxin causes paresthesia and paralysis through interference with neuromuscular conduction.CRISP ThesaurusNational Institutes of Health, 2006
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An aminoperhydroquinazoline poison found mainly in the liver and ovaries of fishes in the order TETRAODONTIFORMES, which are eaten. The toxin causes paresthesia and paralysis through interference with neuromuscular conduction.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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