Pharmacologic Substance
vindesine
[ vin-deh-seen ]
Definitions related to vindesine:
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A synthetic derivative of vinblastine, a naturally occurring vinca alkaloid. Vindesine binds to and stabilizes tubulin, thereby interrupting tubulin polymerization and preventing the formation of the mitotic spindle and cell division; treated cells are unable to undergo mitosis and are arrested in metaphase. This agent also disrupts macromolecular synthesis. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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An anticancer drug that belongs to the family of plant drugs called vinca alkaloids.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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Vinblastine derivative with antineoplastic activity against CANCER. Major side effects are myelosuppression and neurotoxicity. Vindesine is used extensively in chemotherapy protocols (ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS).NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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