Pharmacologic Substance
voriconazole
[ vor-ih-kah-nuh-zole ]
Brand Names:
Vfend
Effect:
Decreased Cell Membrane Integrity; Decreased Cell Membrane Synthesis & Repair
May Treat:
Aspergillosis;
Candidiasis;
Fusariosis
More Information:
Definitions related to voriconazole:
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A drug that treats infections caused by fungi.NCI Dictionary of Cancer TermsU.S. National Cancer Institute, 2021
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A synthetic triazole with antifungal activity. Voriconazole selectively inhibits 14-alpha-lanosterol demethylation in fungi, preventing the production of ergosterol, an essential constituent of the fungal cell membrane, and resulting in fungal cell lysis. (NCI04)NCI ThesaurusU.S. National Cancer Institute, 2021
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A triazole antifungal agent that specifically inhibits STEROL 14-ALPHA-DEMETHYLASE and CYTOCHROME P-450 CYP3A.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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