Pharmacologic Substance
fluconazole Audio
[ floo-kah-nuh-zole ]
Brand Names:
Diflucan
Effect:
Decreased Cell Wall Integrity
May Prevent:
AIDS-Related Opportunistic Infections
May Treat:
AIDS-Related Opportunistic Infections; Blastomycosis; Candidiasis, Chronic Mucocutaneous; Candidiasis, Oral; Candidiasis, Vulvovaginal; Coccidioidomycosis; Fungemia; Histoplasmosis; Meningitis, Cryptococcal; Pneumonia; Urinary Tract Infections
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to fluconazole:
  • A drug that treats infections caused by fungi.
    NCI Dictionary of Cancer Terms
    U.S. National Cancer Institute, 2021
  • A synthetic triazole with antifungal activity. Fluconazole preferentially inhibits fungal cytochrome P-450 sterol C-14 alpha-demethylation, resulting in the accumulation of fungal 14 alpha-methyl sterols, the loss of normal fungal sterols, and fungistatic activity. Mammalian cell demethylation is much less sensitive to fluconazole inhibition.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • Alpha-(2,4-difluorophenyl)-alpha- (1,2,4-triazol-1-ylmethyl)-1,2, 4- triazole-1-ethanol; an antifungal with potential efficacy for patients unable to take amphotericin B or who are immunologically compromised, as in AIDS.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • Triazole antifungal agent that is used to treat oropharyngeal CANDIDIASIS and cryptococcal MENINGITIS in AIDS.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.