Pharmacologic Substance
sotalol
Brand Names:
Betapace; Sorine; Sotylize
Effect:
Arterial Vasodilation; Negative Chronotropy; Negative Inotropy
May Prevent:
Atrial Fibrillation; Atrial Flutter
May Treat:
Atrial Fibrillation; Atrial Flutter; Tachycardia, Supraventricular; Tachycardia, Ventricular; Ventricular Fibrillation
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to sotalol:
  • An adrenergic beta-antagonist that is used in the treatment of life-threatening arrhythmias.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • An ethanolamine derivative with Class III antiarrhythmic and antihypertensive properties. Sotalol is a nonselective beta-adrenergic receptor and potassium channel antagonist. In the heart, this agent inhibits chronotropic and inotropic effects thereby slowing the heart rate and decreasing myocardial contractility. This agent also reduces sinus rate, slows conduction in the atria and in the atrioventricular (AV) node and increases the functional refractory period of the AV node.
    NCI
    U.S. National Cancer Institute, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.