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International Journal of Molecular... Mar 2023Recently, sustainable, biodegradable, and nontoxic materials, especially from renewable resources, have gained a lot of attention, and an important effort has been put...
Recently, sustainable, biodegradable, and nontoxic materials, especially from renewable resources, have gained a lot of attention, and an important effort has been put into the research of biodegradable and biocompatible polymers as an alternative to petroleum-based commodity plastics [...].
Topics: Biodegradation, Environmental; Polymers; Plastics; Biopolymers; Petroleum
PubMed: 37047403
DOI: 10.3390/ijms24076430 -
International Journal of Molecular... Feb 2022Petroleum-based plastics can be found everywhere in our habitual life in diverse applications such as automobiles, aerospace, and medical science [...].
Petroleum-based plastics can be found everywhere in our habitual life in diverse applications such as automobiles, aerospace, and medical science [...].
Topics: Biopolymers; Humans; Petroleum; Plastics
PubMed: 35216374
DOI: 10.3390/ijms23042257 -
International Journal of Molecular... Nov 2023The definition of the term biopolymer is often controversial, and there is no clear distinction between "biopolymers", "bioplastics", and "bio-based polymers" [...].
The definition of the term biopolymer is often controversial, and there is no clear distinction between "biopolymers", "bioplastics", and "bio-based polymers" [...].
Topics: Biopolymers; Polymers
PubMed: 38003441
DOI: 10.3390/ijms242216251 -
International Journal of Molecular... May 2019In recent years, there has been a growing demand for a clean and pollution-free environment and an evident target to minimizing fossil fuel [...].
In recent years, there has been a growing demand for a clean and pollution-free environment and an evident target to minimizing fossil fuel [...].
Topics: Animals; Biopolymers; Costs and Cost Analysis; Renewable Energy
PubMed: 31083389
DOI: 10.3390/ijms20092321 -
International Journal of Molecular... Apr 2022Alginate is an excellent biodegradable and renewable material that is already used for a broad range of industrial applications, including advanced fields, such as... (Review)
Review
Alginate is an excellent biodegradable and renewable material that is already used for a broad range of industrial applications, including advanced fields, such as biomedicine and bioengineering, due to its excellent biodegradable and biocompatible properties. This biopolymer can be produced from brown algae or a microorganism culture. This review presents the principles, chemical structures, gelation properties, chemical interactions, production, sterilization, purification, types, and alginate-based hydrogels developed so far. We present all of the advanced strategies used to remarkably enhance this biopolymer's physicochemical and biological characteristics in various forms, such as injectable gels, fibers, films, hydrogels, and scaffolds. Thus, we present here all of the material engineering enhancement approaches achieved so far in this biopolymer in terms of mechanical reinforcement, thermal and electrical performance, wettability, water sorption and diffusion, antimicrobial activity, in vivo and in vitro biological behavior, including toxicity, cell adhesion, proliferation, and differentiation, immunological response, biodegradation, porosity, and its use as scaffolds for tissue engineering applications. These improvements to overcome the drawbacks of the alginate biopolymer could exponentially increase the significant number of alginate applications that go from the paper industry to the bioprinting of organs.
Topics: Alginates; Biopolymers; Bioprinting; Hydrogels; Tissue Engineering; Tissue Scaffolds
PubMed: 35562876
DOI: 10.3390/ijms23094486 -
Molecules (Basel, Switzerland) Mar 2023Cancer is one of the most prevalent diseases and affects a large proportion of the population worldwide. Conventional treatments in the management include chemotherapy,... (Review)
Review
Cancer is one of the most prevalent diseases and affects a large proportion of the population worldwide. Conventional treatments in the management include chemotherapy, radiotherapy, and surgery. Although being well-accepted, they have many lacunas in the form of severe side effect resulting from lack of targeted delivery. Antibody biopolymer conjugates are a novel method which is an add-on to older methods of immunization. It is used in various diseases and disorders. It ensures the targeted delivery of molecules to increase its efficacy and reduce unwanted effects of the molecule/drug to normal cells. It shows miraculous results in the treatment and management of several cancers even in advanced stages. Herein, we present the chemistry between biopolymer and antibody, their effects on cancer as well as the basic differences between antibody-drug conjugates and antibody-biopolymer conjugates.
Topics: Humans; Antibodies; Neoplasms; Medical Oncology; Immunoconjugates; Biopolymers; Antineoplastic Agents
PubMed: 36985578
DOI: 10.3390/molecules28062605 -
International Journal of Molecular... Jul 2020Oil-derived plastics are the most commonly used materials for packaging because of their features, low cost, and availability of resources for manufacturing [...].
Oil-derived plastics are the most commonly used materials for packaging because of their features, low cost, and availability of resources for manufacturing [...].
Topics: Biopolymers; Food Packaging; Green Chemistry Technology
PubMed: 32668678
DOI: 10.3390/ijms21144942 -
Enzyme and Microbial Technology Oct 2021Encapsulated enzymes are stable under various conditions and used in enzyme therapy, catalysis, and biosensors. The capsules are often inspired by structures from nature... (Review)
Review
Encapsulated enzymes are stable under various conditions and used in enzyme therapy, catalysis, and biosensors. The capsules are often inspired by structures from nature such as viral capsids, DNA motifs and diatom frustules. They are based on inorganic minerals as well as soft or polymeric materials, or even a combination of these. The choice of material influences the enzyme loading and response to heat, pH and presence of proteases. This review provides a comparison of enzyme encapsulation based on these different principles with a focus on materials inspired by nature.
Topics: Biomimetics; Biopolymers; Capsules; Catalysis; Polymers; Silicon Dioxide
PubMed: 34489023
DOI: 10.1016/j.enzmictec.2021.109864 -
Advances in Clinical and Experimental... Sep 2022There are numerous surprising discoveries in current comprehensive biopolymer research, including the description of new types of biopolymers and the extension of their...
There are numerous surprising discoveries in current comprehensive biopolymer research, including the description of new types of biopolymers and the extension of their applications. The discovery of a new rotifer-specific biopolymer family (Rotimers) and the exceptional ability of these micrometazoans to inactivate and catabolize human-type neurotoxic aggregates (e.g., beta-amyloids, alpha-synucleins, prions) by their exudates can be mentioned as the original work of our research group. Rotimers are exogenous and protein complex molecules with a calcium-dependent production mechanism in both bdelloid and monogonant rotifers. However, their experimental and application possibilities are still unknown; only part of the class has been explored and described. Current Rotimer-related studies present promising biodiversity and bioactivity of these biomaterials (e.g., antiand disaggregation effects or high degrees of adhesion to other molecules). The primary objective of current research is to explore and develop their application in translational biomedicine. A key area is the design of drug candidates against neurodegeneration-related aggregates based on the molecular information provided by the composition, structure and function of Rotimers. These novel biomaterials have the potential to open new perspectives in the pharmaceutical industry and healthcare.
Topics: Animals; Biocompatible Materials; Biopolymers; Calcium; Humans; Prions; Rotifera; Synucleins
PubMed: 36000877
DOI: 10.17219/acem/152430 -
Analytical Biochemistry Sep 2022Multi-wavelength analytical ultracentrifugation (MW-AUC) is a recent development made possible by new analytical ultracentrifuge optical systems. MW-AUC extends the... (Review)
Review
Multi-wavelength analytical ultracentrifugation (MW-AUC) is a recent development made possible by new analytical ultracentrifuge optical systems. MW-AUC extends the basic hydrodynamic information content of AUC and provides access to a wide range of new applications for biopolymer characterization, and is poised to become an essential analytical tool to study macromolecular interactions. It adds an orthogonal spectral dimension to the traditional hydrodynamic characterization by exploiting unique chromophores in analyte mixtures that may or may not interact. Here we illustrate the utility of MW-AUC for experimental investigations where the benefit of the added spectral dimension provides critical information that is not accessible, and impossible to resolve with traditional AUC methods. We demonstrate the improvements in resolution and information content obtained by this technique compared to traditional single- or dual-wavelength approaches, and discuss experimental design considerations and limitations of the method. We further address the advantages and disadvantages of the two MW optical systems available today, and the differences in data analysis strategies between the two systems.
Topics: Biopolymers; Hydrodynamics; Ultracentrifugation
PubMed: 35609686
DOI: 10.1016/j.ab.2022.114728