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Annals of Internal Medicine Jul 2012Although approximately 85 million units of red blood cells (RBCs) are transfused annually worldwide, transfusion practices vary widely. The AABB (formerly, the American... (Review)
Review
DESCRIPTION
Although approximately 85 million units of red blood cells (RBCs) are transfused annually worldwide, transfusion practices vary widely. The AABB (formerly, the American Association of Blood Banks) developed this guideline to provide clinical recommendations about hemoglobin concentration thresholds and other clinical variables that trigger RBC transfusions in hemodynamically stable adults and children.
METHODS
These guidelines are based on a systematic review of randomized clinical trials evaluating transfusion thresholds. We performed a literature search from 1950 to February 2011 with no language restrictions. We examined the proportion of patients who received any RBC transfusion and the number of RBC units transfused to describe the effect of restrictive transfusion strategies on RBC use. To determine the clinical consequences of restrictive transfusion strategies, we examined overall mortality, nonfatal myocardial infarction, cardiac events, pulmonary edema, stroke, thromboembolism, renal failure, infection, hemorrhage, mental confusion, functional recovery, and length of hospital stay. RECOMMENDATION 1: The AABB recommends adhering to a restrictive transfusion strategy (7 to 8 g/dL) in hospitalized, stable patients (Grade: strong recommendation; high-quality evidence). RECOMMENDATION 2: The AABB suggests adhering to a restrictive strategy in hospitalized patients with preexisting cardiovascular disease and considering transfusion for patients with symptoms or a hemoglobin level of 8 g/dL or less (Grade: weak recommendation; moderate-quality evidence). RECOMMENDATION 3: The AABB cannot recommend for or against a liberal or restrictive transfusion threshold for hospitalized, hemodynamically stable patients with the acute coronary syndrome (Grade: uncertain recommendation; very low-quality evidence). RECOMMENDATION 4: The AABB suggests that transfusion decisions be influenced by symptoms as well as hemoglobin concentration (Grade: weak recommendation; low-quality evidence).
Topics: Acute Coronary Syndrome; Adult; Blood Banks; Child; Decision Support Techniques; Erythrocyte Transfusion; Guideline Adherence; Hemoglobin A; Hospitalization; Humans; Randomized Controlled Trials as Topic; United States
PubMed: 22751760
DOI: 10.7326/0003-4819-157-1-201206190-00429 -
Revista Medica Del Instituto Mexicano... Jan 2023In 2022, 2 years on from the start of the pandemic, the Instituto Mexicano del Seguro Social (IMSS, Mexican Institute for Social Security) has been reorganizing its...
In 2022, 2 years on from the start of the pandemic, the Instituto Mexicano del Seguro Social (IMSS, Mexican Institute for Social Security) has been reorganizing its services at full, out of which blood banks play a key role. In addition, on June 14 it is celebrated the World Blood Donor Day by the World Health Organization and this year Mexico was the host country for the celebration. Therefore, it is important to highlight the work carried out in blood banks, ranging from their main activity, which is the recruitment of blood donors and the blood components production, to the different interventions they have in the field of transplantation, diseases emerging diagnosis and the development of new therapeutic modalities, such as, for example, cell therapy.
Topics: Humans; Academies and Institutes; Blood Banks; Blood Donors; Mexico; Social Security
PubMed: 36377981
DOI: No ID Found -
Clinics in Laboratory Medicine Dec 2020SARS-CoV-2 (also known as COVID-19) has been an unprecedented challenge in many parts of the medical field with blood banking being no exception. COVID-19 has had a... (Review)
Review
SARS-CoV-2 (also known as COVID-19) has been an unprecedented challenge in many parts of the medical field with blood banking being no exception. COVID-19 has had a distinctly negative effect on our blood collection nationwide forcing blood banks, blood centers, and the US government to adopt new policies to adapt to a decreased blood supply as well as to protect our donors from COVID-19. These policies can be seen distinctly in patient blood management and blood bank operations. We are also faced with developing policies and procedures for a nontraditional therapy, convalescent plasma; its efficacy and safety is still not completely elucidated as of yet.
Topics: Betacoronavirus; Blood Banks; Blood Donors; Blood Safety; Blood Transfusion; COVID-19; Coronavirus Infections; Humans; Infection Control; Pandemics; Pneumonia, Viral; Policy Making; SARS-CoV-2; Transfusion Medicine; Blood Banking
PubMed: 33121624
DOI: 10.1016/j.cll.2020.08.013 -
Journal of Clinical Pathology Apr 1995
Review
Topics: Blood Banks; Blood Transfusion; Canada; Humans; Medical Audit; Practice Guidelines as Topic
PubMed: 7615842
DOI: 10.1136/jcp.48.4.283 -
Turkish Journal of Haematology :... Feb 2022Hematologists often encounter transfusion problems, one of which is crossmatch incompatibility. In many countries, transfusion medicine is not a recognized specialty,... (Review)
Review
Hematologists often encounter transfusion problems, one of which is crossmatch incompatibility. In many countries, transfusion medicine is not a recognized specialty, there are no reference immunohematology laboratories, and most blood banks can only perform “type and screen” and crossmatch analyses. Therefore, hematologists should have basic knowledge about blood banking procedures and how to use them. This review aims to provide hematologists who do not have access to advanced blood bank laboratories some practical tips for handling problems in pretransfusion testing.
Topics: Blood Banks; Blood Grouping and Crossmatching; Blood Transfusion; Humans; Transfusion Medicine
PubMed: 34886658
DOI: 10.4274/tjh.galenos.2021.2021.0544 -
Journal of Medicine and Life Jun 2022Cord blood is a rich source of hematopoietic stem cells used to treat many diseases of blood origin. Thus, storage banks were created to store and provide umbilical cord... (Review)
Review
Cord blood is a rich source of hematopoietic stem cells used to treat many diseases of blood origin. Thus, storage banks were created to store and provide umbilical cord cells. With the development of diagnostic and therapeutic technologies and techniques in medicine, ethical issues have also become more widespread and complex. After the creation of the cord blood banks, efforts were made to address the ethical issues associated with such banks. The present study attempts to identify the ethical challenges in these banks in the published studies. Databases including PubMed, Scopus, Web of Science (WOS), Embase, Proquest, and Google Scholar were searched from January 1996 to January 2021. Then, the ethical challenges of the cord blood bank were extracted from the results section using thematic content analysis. 22 studies were selected based on inclusion and exclusion criteria. The ethical challenges raised in the studies included private or public ownership of the bank, fair access to banking services, informed and voluntary consent, failure to provide sufficient information to individuals about the process, confidentiality of user's information, conflict of interest of bank founders (who are commonly doctors). The findings of this study indicated that there are serious ethical concerns regarding umbilical cord blood banks. Responding clearly to these ethical challenges calls for the attention of policymakers and medical ethics professionals; this will require a clear statement of the various aspects of these banks for society.
Topics: Blood Banks; Fetal Blood; Humans; Ownership
PubMed: 35928362
DOI: 10.25122/jml-2021-0162 -
Tidsskrift For Den Norske Laegeforening... Aug 2022
Topics: Blood Banks; Humans; Surveys and Questionnaires; Travel
PubMed: 35997184
DOI: 10.4045/tidsskr.22.0469 -
Pediatrics Nov 2017This policy statement is intended to provide information to guide pediatricians, obstetricians, and other medical specialists and health care providers in responding to... (Review)
Review
This policy statement is intended to provide information to guide pediatricians, obstetricians, and other medical specialists and health care providers in responding to parents' questions about cord blood donation and banking as well as the types (public versus private) and quality of cord blood banks. Cord blood is an excellent source of stem cells for hematopoietic stem cell transplantation in children with some fatal diseases. Cord blood transplantation offers another method of definitive therapy for infants, children, and adults with certain hematologic malignancies, hemoglobinopathies, severe forms of T-lymphocyte and other immunodeficiencies, and metabolic diseases. The development of universal screening for severe immunodeficiency assay in a growing number of states is likely to increase the number of cord blood transplants. Both public and private cord blood banks worldwide hold hundreds of thousands of cord blood units designated for the treatment of fatal or debilitating illnesses. The procurement, characterization, and cryopreservation of cord blood is free for families who choose public banking. However, the family cost for private banking is significant and not covered by insurance, and the unit may never be used. Quality-assessment reviews by several national and international accrediting bodies show private cord blood banks to be underused for treatment, less regulated for quality control, and more expensive for the family than public cord blood banks. There is an unquestionable need to study the use of cord blood banking to make new and important alternative means of reconstituting the hematopoietic blood system in patients with malignancies and blood disorders and possibly regenerating tissue systems in the future. Recommendations regarding appropriate ethical and operational standards (including informed consent policies, financial disclosures, and conflict-of-interest policies) are provided for physicians, institutions, and organizations that operate or have a relationship with cord blood banking programs. The information on all aspects of cord blood banking gathered in this policy statement will facilitate parental choice for public or private cord blood banking.
Topics: Academies and Institutes; Blood Banks; Child; Cord Blood Stem Cell Transplantation; Fetal Blood; Health Policy; Hematologic Diseases; Humans; Pediatrics; United States
PubMed: 29084832
DOI: 10.1542/peds.2017-2695 -
Tidsskrift For Den Norske Laegeforening... Feb 2018
Topics: Blood Banks; Humans; Norway; Prenatal Diagnosis
PubMed: 29460564
DOI: 10.4045/tidsskr.18.0144 -
Revista Medica Del Instituto Mexicano... Jan 2023Medicine has had a vertiginous advance in the last two centuries. After the first successful transfusions, transfusional medicine and blood banks arose. The ladder... (Review)
Review
Medicine has had a vertiginous advance in the last two centuries. After the first successful transfusions, transfusional medicine and blood banks arose. The ladder perform vital functions, from donor screening to the studies for the analysis of blood that are carried out before its use for transfusion and the follow-up of patients who receive blood components. Molecular biology is highly relevant in these activities, since it has allowed the reduction of window periods for the detection of diseases transmissible by blood; it has allowed the complete study of the typing of blood groups and HLA molecules, and it has allowed the adequate phenotypic interpretation of patients and donors by being able to have their genotype. The most relevant impact of the implementation of molecular biology techniques was the screening for the detection of transfusion-transmissible diseases in blood donors, which has allowed improving the safety of the components obtained. Molecular biology techniques applied in the study of the donor-recipient have allowed better care of patients who have required a transfusion or transplant. In this work, it is reviewed the importance of molecular biology in blood banks, with which the care for the Instituto Mexicano del Seguro Social beneficiaries has improved, as well as for the blood donors who are mostly not insured.
Topics: Humans; Blood Banks; Blood Donors; Blood Transfusion; Donor Selection; Molecular Biology
PubMed: 36378106
DOI: No ID Found