-
Revista Medica Del Instituto Mexicano... Jan 2023In 2022, 2 years on from the start of the pandemic, the Instituto Mexicano del Seguro Social (IMSS, Mexican Institute for Social Security) has been reorganizing its...
In 2022, 2 years on from the start of the pandemic, the Instituto Mexicano del Seguro Social (IMSS, Mexican Institute for Social Security) has been reorganizing its services at full, out of which blood banks play a key role. In addition, on June 14 it is celebrated the World Blood Donor Day by the World Health Organization and this year Mexico was the host country for the celebration. Therefore, it is important to highlight the work carried out in blood banks, ranging from their main activity, which is the recruitment of blood donors and the blood components production, to the different interventions they have in the field of transplantation, diseases emerging diagnosis and the development of new therapeutic modalities, such as, for example, cell therapy.
Topics: Humans; Academies and Institutes; Blood Banks; Blood Donors; Mexico; Social Security
PubMed: 36377981
DOI: No ID Found -
Biological Chemistry Jun 2015Anemia and hemorrhagic shock are leading causes of morbidity and mortality worldwide, and transfusion of human blood products is the ideal treatment for these... (Review)
Review
Anemia and hemorrhagic shock are leading causes of morbidity and mortality worldwide, and transfusion of human blood products is the ideal treatment for these conditions. As human erythrocytes age during storage in blood banks they undergo many biochemical and structural changes, termed the red blood cell 'storage lesion'. Specifically, ATP and pH levels decrease as metabolic end products, oxidative stress, cytokines, and cell-free hemoglobin increase. Also, membrane proteins and lipids undergo conformational and organizational changes that result in membrane loss, viscoelastic changes and microparticle formation. As a result, transfusion of aged blood is associated with a host of adverse consequences such as decreased tissue perfusion, increased risk of infection, and increased mortality. This review summarizes current research detailing the known parts of the erythrocyte storage lesion and their physiologic consequences.
Topics: Blood Banks; Cytokines; Erythrocyte Aging; Erythrocytes; Hemoglobins; Humans; Oxidative Stress
PubMed: 25803075
DOI: 10.1515/hsz-2014-0292 -
Transfusion Clinique Et Biologique :... May 2024The field of haemovigilance continues to develop, building on more than forty years of international experience. This review considers the current scope and activities... (Review)
Review
The field of haemovigilance continues to develop, building on more than forty years of international experience. This review considers the current scope and activities of haemovigilance around the world and explores aspects of preparation for the advent of new blood products and alternative therapies to transfusion; new tools for data acquisition (including patient- and donor-reported outcomes, and data from 'wearables') and the analysis and communication of haemovigilance results.
Topics: Humans; Blood Safety; Blood Transfusion; Blood Banks; Blood Donors; Forecasting
PubMed: 38460837
DOI: 10.1016/j.tracli.2024.03.001 -
Tidsskrift For Den Norske Laegeforening... Feb 2018
Topics: Blood Banks; Humans; Norway; Prenatal Diagnosis
PubMed: 29460564
DOI: 10.4045/tidsskr.18.0144 -
Annals of Laboratory Medicine May 2022Blood is lifesaving; however, it can neither be limitlessly acquired nor artificially produced. The supply and use of blood, as an invaluable biological commodity,... (Review)
Review
Blood is lifesaving; however, it can neither be limitlessly acquired nor artificially produced. The supply and use of blood, as an invaluable biological commodity, necessitate systematic and rational management under governmental guidance to ensure safe and reliable transfusions. Despite Korea's blood donation rate of 5.04%, which is higher than the 3.15% in high-income countries as reported by the WHO, the demand for blood exceeds the availability. This is due to the birthrate decline, dearth of young donors, and growing and aging recipient population. This review outlines the Korean blood management system, with a focus on blood service data from 2020, with the aim to delineate the current state of Korea's blood management system and the policies established to address the imminent blood shortage. Each policy is described in detail to provide helpful information for blood management services in other countries.
Topics: Blood Banks; Humans; Republic of Korea
PubMed: 34907100
DOI: 10.3343/alm.2022.42.3.306 -
Journal of Medicine and Life Jun 2022Cord blood is a rich source of hematopoietic stem cells used to treat many diseases of blood origin. Thus, storage banks were created to store and provide umbilical cord... (Review)
Review
Cord blood is a rich source of hematopoietic stem cells used to treat many diseases of blood origin. Thus, storage banks were created to store and provide umbilical cord cells. With the development of diagnostic and therapeutic technologies and techniques in medicine, ethical issues have also become more widespread and complex. After the creation of the cord blood banks, efforts were made to address the ethical issues associated with such banks. The present study attempts to identify the ethical challenges in these banks in the published studies. Databases including PubMed, Scopus, Web of Science (WOS), Embase, Proquest, and Google Scholar were searched from January 1996 to January 2021. Then, the ethical challenges of the cord blood bank were extracted from the results section using thematic content analysis. 22 studies were selected based on inclusion and exclusion criteria. The ethical challenges raised in the studies included private or public ownership of the bank, fair access to banking services, informed and voluntary consent, failure to provide sufficient information to individuals about the process, confidentiality of user's information, conflict of interest of bank founders (who are commonly doctors). The findings of this study indicated that there are serious ethical concerns regarding umbilical cord blood banks. Responding clearly to these ethical challenges calls for the attention of policymakers and medical ethics professionals; this will require a clear statement of the various aspects of these banks for society.
Topics: Blood Banks; Fetal Blood; Humans; Ownership
PubMed: 35928362
DOI: 10.25122/jml-2021-0162 -
Clinics in Laboratory Medicine Dec 2020SARS-CoV-2 (also known as COVID-19) has been an unprecedented challenge in many parts of the medical field with blood banking being no exception. COVID-19 has had a... (Review)
Review
SARS-CoV-2 (also known as COVID-19) has been an unprecedented challenge in many parts of the medical field with blood banking being no exception. COVID-19 has had a distinctly negative effect on our blood collection nationwide forcing blood banks, blood centers, and the US government to adopt new policies to adapt to a decreased blood supply as well as to protect our donors from COVID-19. These policies can be seen distinctly in patient blood management and blood bank operations. We are also faced with developing policies and procedures for a nontraditional therapy, convalescent plasma; its efficacy and safety is still not completely elucidated as of yet.
Topics: Betacoronavirus; Blood Banks; Blood Donors; Blood Safety; Blood Transfusion; COVID-19; Coronavirus Infections; Humans; Infection Control; Pandemics; Pneumonia, Viral; Policy Making; SARS-CoV-2; Transfusion Medicine; Blood Banking
PubMed: 33121624
DOI: 10.1016/j.cll.2020.08.013 -
Turkish Journal of Haematology :... Feb 2022Hematologists often encounter transfusion problems, one of which is crossmatch incompatibility. In many countries, transfusion medicine is not a recognized specialty,... (Review)
Review
Hematologists often encounter transfusion problems, one of which is crossmatch incompatibility. In many countries, transfusion medicine is not a recognized specialty, there are no reference immunohematology laboratories, and most blood banks can only perform “type and screen” and crossmatch analyses. Therefore, hematologists should have basic knowledge about blood banking procedures and how to use them. This review aims to provide hematologists who do not have access to advanced blood bank laboratories some practical tips for handling problems in pretransfusion testing.
Topics: Blood Banks; Blood Grouping and Crossmatching; Blood Transfusion; Humans; Transfusion Medicine
PubMed: 34886658
DOI: 10.4274/tjh.galenos.2021.2021.0544 -
Blood bank storage of red blood cells increases RBC cytoplasmic membrane order and bending rigidity.PloS One 2021Blood banks around the world store blood components for several weeks ensuring its availability for transfusion medicine. Red blood cells (RBCs) are known to undergo...
Blood banks around the world store blood components for several weeks ensuring its availability for transfusion medicine. Red blood cells (RBCs) are known to undergo compositional changes during storage, which may impact the cells' function and eventually the recipients' health. We extracted the RBC's cytoplasmic membrane (RBCcm) to study the effect of storage on the membranes' molecular structure and bending rigidity by a combination of X-ray diffraction (XRD), X-ray diffuse scattering (XDS) and coarse grained Molecular Dynamics (MD) simulations. Blood was stored in commercial blood bags for 2 and 5 weeks, respectively and compared to freshly drawn blood. Using mass spectrometry, we measured an increase of fatty acids together with a slight shift towards shorter tail lengths. We observe an increased fraction (6%) of liquid ordered (lo) domains in the RBCcms with storage time, and an increased lipid packing in these domains, leading to an increased membrane thickness and membrane order. The size of both, lo and liquid disordered (ld) lipid domains was found to decrease with increased storage time by up to 25%. XDS experiments reveal a storage dependent increase in the RBCcm's bending modulus κ by a factor of 2.8, from 1.9 kBT to 5.3 kBT. MD simulations were conducted in the absence of proteins. The results show that the membrane composition has a small contribution to the increased bending rigidity and suggests additional protein-driven mechanisms.
Topics: Blood Preservation; Cell Membrane; Erythrocytes; Molecular Dynamics Simulation
PubMed: 34767588
DOI: 10.1371/journal.pone.0259267 -
Hematology, Transfusion and Cell Therapy 2019Infection by Trypanosoma cruzi is challenging to blood bank supplies in terms of accurate diagnosis, mostly due to its clinical complexity. Infected individuals may... (Review)
Review
INTRODUCTION
Infection by Trypanosoma cruzi is challenging to blood bank supplies in terms of accurate diagnosis, mostly due to its clinical complexity. Infected individuals may remain asymptomatic for years, albeit they may have circulating parasites potentially transferable to eventual receptors of a transfusion.
OBJECTIVE
Although risk donors are systematically excluded through a survey, an important residual risk for transmission remains, evidencing the need to implement additional actions for the detection of T. cruzi in blood banks.
METHOD
A review of the scientific literature is presented with the objective of identifying relevant publications on this subject.
RESULTS
We discuss the diagnostic considerations of this chronic infection on transfusion medicine and some recent advances in the processing of blood and derivatives units.
CONCLUSION
Finally, recommendations are made on how the transmission of T. cruzi can be avoided through the implementation of better diagnostic and pathogen control measures at blood banks.
PubMed: 31085149
DOI: 10.1016/j.htct.2018.12.001