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Nature Reviews. Microbiology Aug 2011Imaging mass spectrometry tools allow the two-dimensional visualization of the distribution of trace metals, metabolites, surface lipids, peptides and proteins directly... (Review)
Review
Imaging mass spectrometry tools allow the two-dimensional visualization of the distribution of trace metals, metabolites, surface lipids, peptides and proteins directly from biological samples without the need for chemical tagging or antibodies, and are becoming increasingly useful for microbiology applications. These tools, comprising different imaging mass spectrometry techniques, are ushering in an exciting new era of discovery by enabling the generation of chemical hypotheses based on the spatial mapping of atoms and molecules that can correlate to or transcend observed phenotypes. In this Innovation article, we explore the wide range of imaging mass spectrometry techniques that is available to microbiologists and describe the unique applications of these tools to microbiology with respect to the types of samples to be investigated.
Topics: Image Processing, Computer-Assisted; Mass Spectrometry; Microbiology
PubMed: 21822293
DOI: 10.1038/nrmicro2634 -
Molecular Oral Microbiology Aug 2015
Topics: History, 20th Century; History, 21st Century; Host-Pathogen Interactions; Microbiology; Mouth; United States
PubMed: 26059907
DOI: 10.1111/omi.12105 -
Nihon Saikingaku Zasshi. Japanese... 2021
Topics: Education, Distance; Humans; Microbiology
PubMed: 33627526
DOI: 10.3412/jsb.76.125 -
International Microbiology : the... Sep 2018Over geologic time, the water in the Bonneville basin has risen and fallen, most dramatically as freshwater Lake Bonneville lost enormous volume 15,000-13,000 years... (Review)
Review
Over geologic time, the water in the Bonneville basin has risen and fallen, most dramatically as freshwater Lake Bonneville lost enormous volume 15,000-13,000 years ago and became the modern day Great Salt Lake. It is likely that paleo-humans lived along the shores of this body of water as it shrunk to the present margins, and native peoples inhabited the surrounding desert and wetlands in recent times. Nineteenth century Euro-American explorers and pioneers described the geology, geography, and flora and fauna of Great Salt Lake, but their work attracted white settlers to Utah, who changed the lake immeasurably. Human intervention in the 1950s created two large sub-ecosystems, bisected by a railroad causeway. The north arm approaches ten times the salinity of sea water, while the south arm salinity is a meager four times that of the oceans. Great Salt Lake was historically referred to as sterile, leading to the nickname "America's Dead Sea." However, the salty brine is teaming with life, even in the hypersaline north arm. In fact, scientists have known that this lake contains a diversity of microscopic lifeforms for more than 100 years. This essay will explore the stories of the people who observed and researched the salty microbiology of Great Salt Lake, whose discoveries demonstrated the presence of bacteria, archaea, algae, and protozoa that thrive in this lake. These scientists documented the lake's microbiology as the lake changed, with input from human waste and the creation of impounded areas. Modern work on the microbiology of Great Salt Lake has added molecular approaches and illuminated the community structures in various regions, and fungi and viruses have now been described. The exploration of Great Salt Lake by scientists describing these tiny inhabitants of the brine illuminate the larger terminal lake with its many facets, anthropomorphic challenges, and ever-changing shorelines.
Topics: Biota; History, 20th Century; History, 21st Century; Humans; Lakes; Microbiology; Salinity; Utah
PubMed: 30810951
DOI: 10.1007/s10123-018-0008-z -
MBio Aug 2016The American Academy of Microbiology convened a colloquium to discuss problems in the biological sciences, with emphasis on identifying mechanisms to improve the quality...
The American Academy of Microbiology convened a colloquium to discuss problems in the biological sciences, with emphasis on identifying mechanisms to improve the quality of research. Participants from various disciplines made six recommendations: (i) design rigorous and comprehensive evaluation criteria to recognize and reward high-quality scientific research; (ii) require universal training in good scientific practices, appropriate statistical usage, and responsible research practices for scientists at all levels, with training content regularly updated and presented by qualified scientists; (iii) establish open data at the timing of publication as the standard operating procedure throughout the scientific enterprise; (iv) encourage scientific journals to publish negative data that meet methodologic standards of quality; (v) agree upon common criteria among scientific journals for retraction of published papers, to provide consistency and transparency; and (vi) strengthen research integrity oversight and training. These recommendations constitute an actionable framework that, in combination, could improve the quality of biological research.
Topics: Biomedical Research; Microbiological Techniques; Microbiology; Quality Control
PubMed: 27578756
DOI: 10.1128/mBio.01256-16 -
Comptes Rendus Biologies Nov 2022Pasteur's originality in the way he developed pure research is to have understood the importance, for society, of the underlying motivation. Curiosity, of course, is a...
Pasteur's originality in the way he developed pure research is to have understood the importance, for society, of the underlying motivation. Curiosity, of course, is a strong motivation, which explains why we seek to understand the origin of life. But, in front of the immensity of the possible choices, why not, also, choose to start from questions of economic interest (diseases of beer and wine, diseases affecting the silk industry ...) Finally, of course, health is a constant preoccupation, but the diseases, which have no borders, often come from tropical countries and Asia especially. It is therefore necessary to settle there, but not to come and impose one's point of view, but on the contrary to use the knowledge coming from the local culture in order to open new ways of understanding the reality of the world.
Topics: Microbiology; Research
PubMed: 36852600
DOI: 10.5802/crbiol.89 -
Microbiology (Reading, England) Jul 2022
Topics: Microbiology; Soil Microbiology
PubMed: 35904846
DOI: 10.1099/mic.0.001234 -
Revista Argentina de Microbiologia 2017
Topics: Food Microbiology; Mycology
PubMed: 29162231
DOI: 10.1016/j.ram.2017.10.001 -
Microbiology (Reading, England) May 2021
Topics: Bacteria; Microbiology; Minerals; Online Systems
PubMed: 33945459
DOI: 10.1099/mic.0.001061 -
FEMS Microbiology Letters Oct 2016
Topics: Career Choice; Chemistry; Female; France; History, 20th Century; History, 21st Century; Humans; Microbiology
PubMed: 27624306
DOI: 10.1093/femsle/fnw215