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Biology Dec 2020Professional athletes are expected to continuously improve their performance, and some might also use illegal methods-e.g., autologous blood doping (ABD)-to achieve... (Review)
Review
Professional athletes are expected to continuously improve their performance, and some might also use illegal methods-e.g., autologous blood doping (ABD)-to achieve improvements. This article applies a systematic literature review to investigate differences in the ABD methods and the related performance and blood parameters owing to different storage conditions-cryopreservation (CP) and cold storage (CS)-and different storage durations. The literature research resulted in 34 original articles. The majority of currently published studies employed CS during ABD. This contrasts to the applied storage technique in professional sports, which was mainly reported to be CP. The second outcome of the literature research revealed large differences in the storage durations applied, which were in the range of one day to 17 weeks between blood sampling and re-infusion, which might affect recovery of the red blood cell mass and thus performance outcome related to ABD. Data revealed that performance parameters were positively affected by ABD when a minimal storage duration of four weeks was adhered. This article identified a need for further research that reflect common ABD practice and its real effects on performance parameters, but also on related blood parameters in order to develop valid and reliable ABD detection methods.
PubMed: 33383643
DOI: 10.3390/biology10010014 -
Nano-micro Letters Jun 2022Simultaneously improving the energy density and power density of electrochemical energy storage systems is the ultimate goal of electrochemical energy storage... (Review)
Review
Simultaneously improving the energy density and power density of electrochemical energy storage systems is the ultimate goal of electrochemical energy storage technology. An effective strategy to achieve this goal is to take advantage of the high capacity and rapid kinetics of electrochemical proton storage to break through the power limit of batteries and the energy limit of capacitors. This article aims to review the research progress on the physicochemical properties, electrochemical performance, and reaction mechanisms of electrode materials for electrochemical proton storage. According to the different charge storage mechanisms, the surface redox, intercalation, and conversion materials are classified and introduced in detail, where the influence of crystal water and other nanostructures on the migration kinetics of protons is clarified. Several reported advanced full cell devices are summarized to promote the commercialization of electrochemical proton storage. Finally, this review provides a framework for research directions of charge storage mechanism, basic principles of material structure design, construction strategies of full cell device, and goals of practical application for electrochemical proton storage.
PubMed: 35699769
DOI: 10.1007/s40820-022-00864-y -
Physiology (Bethesda, Md.) Apr 2010The discovery over five decades ago of the lysosome, as a degradative organelle and its dysfunction in lysosomal storage disorder patients, was both insightful and... (Review)
Review
The discovery over five decades ago of the lysosome, as a degradative organelle and its dysfunction in lysosomal storage disorder patients, was both insightful and simple in concept. Here, we review some of the history and pathophysiology of lysosomal storage disorders to show how they have impacted on our knowledge of lysosomal biology. Although a significant amount of information has been accrued on the molecular genetics and biochemistry of lysosomal storage disorders, we still do not fully understand the mechanistic link between the storage material and disease pathogenesis. However, the accumulation of undegraded substrate(s) can disrupt other lysosomal degradation processes, vesicular traffic, and lysosomal biogenesis to evoke the diverse pathophysiology that is evident in this complex set of disorders.
Topics: Humans; Lysosomal Storage Diseases; Lysosomes
PubMed: 20430954
DOI: 10.1152/physiol.00041.2009 -
Heliyon Dec 2022This study was conducted to evaluate the effect of storage materials (Storage bags) and durations on seed quality and proximate composition of emmer wheat in farmer...
This study was conducted to evaluate the effect of storage materials (Storage bags) and durations on seed quality and proximate composition of emmer wheat in farmer storage practices. The emmer wheat samples were stored for nine consecutive months in PICS (Purdue Improved Crop Storage) bag (PB), Grainpro® Bag (GPB), Polypropylene Bag (PPB), emmer wheat treated with Filter Cake (a byproduct of Aluminum Sulphate factory) (FC), stored in Polypropylene bag (PPBFC) and Emmer wheat treated with triplex (a by-product of soap factory) (TX) stored in Polypropylene bag (PPBTX). Data on seed quality and proximate composition were evaluated every three months' interval for 9 months. As storage period increased from three to nine months; Germination Percentage, Speed of Germination, Vigour, Thousand Seed Weight (TSW), Bulk Density (BD), Seed Damage%, Seed Weight Loss, Protein and Carbohydrate contents were significantly influenced by the interaction effect of storage period and storage bag used. The highest germination (98%) was recorded from seeds stored in GPB for three months. The protein content of grains stored in GPB for three months showed the highest (8.3%) whereas, the lowest (6.5%) was for PPB at nine months of storage. Minimal insect incidence and lower seed weight loss were observed in emmer wheat stored in bags such as BP, GPB, PPBFC, and PPBTX. The use of PB and GPB, as well as the application of FC and TX maintained the proximate and seed quality of emmer wheat.
PubMed: 36593817
DOI: 10.1016/j.heliyon.2022.e12506 -
IScience Mar 2023DNA Encoding, as a key step in DNA storage, plays an important role in reading and writing accuracy and the storage error rate. However, currently, the encoding...
DNA Encoding, as a key step in DNA storage, plays an important role in reading and writing accuracy and the storage error rate. However, currently, the encoding efficiency is not high enough and the encoding speed is not fast enough, which limits the performance of DNA storage systems. In this work, a DNA storage encoding system with a graph convolutional network and self-attention (GCNSA) is proposed. The experimental results show that DNA storage code constructed by GCNSA increases by 14.4% on average under the basic constraints, and by 5%-40% under other constraints. The increase of DNA storage codes effectively improves the storage density of 0.7-2.2% in the DNA storage system. The GCNSA predicted more DNA storage codes in less time while ensuring the quality of codes, which lays a foundation for higher read and write efficiency in DNA storage.
PubMed: 36876131
DOI: 10.1016/j.isci.2023.106231 -
GigaScience Jun 2019The information explosion has led to a rapid increase in the amount of data requiring physical storage. However, in the near future, existing storage methods (i.e.,... (Review)
Review
The information explosion has led to a rapid increase in the amount of data requiring physical storage. However, in the near future, existing storage methods (i.e., magnetic and optical media) will be insufficient to store these exponentially growing data. Therefore, data scientists are continually looking for better, more stable, and space-efficient alternatives to store these huge datasets. Because of its unique biological properties, highly condensed DNA has great potential to become a storage material for the future. Indeed, DNA-based data storage has recently emerged as a promising approach for long-term digital information storage. This review summarizes state-of-the-art methods, including digital-to-DNA coding schemes and the media types used in DNA-based data storage, and provides an overview of recent progress achieved in this field and its exciting future.
Topics: DNA; Information Storage and Retrieval
PubMed: 31220251
DOI: 10.1093/gigascience/giz075 -
Journal of Veterinary Internal Medicine 2002Lysosomal storage diseases are rare, inherited disorders caused by the deficiency of 1 or more enzymes within the lysosomes of cells or by the deficiency of an... (Review)
Review
Lysosomal storage diseases are rare, inherited disorders caused by the deficiency of 1 or more enzymes within the lysosomes of cells or by the deficiency of an activating protein or cofactor necessary for enzyme activity. The enzyme deficiency leads to a catabolic blockade and subsequent accumulation of storage material, and this in turn leads, albeit indirectly, to a wide array of clinical signs. Many features of storage diseases make them difficult to recognize and diagnose. In this review, we summarize the clinical features of these diseases and outline the steps required to confirm a diagnosis.
Topics: Animals; Biopsy; Cat Diseases; Cats; Dog Diseases; Dogs; Lysosomal Storage Diseases; Lysosomes
PubMed: 11899921
DOI: 10.1892/0891-6640(2002)016<0133:radols>2.3.co;2 -
Injury Epidemiology Dec 2022Firearm injury is a leading cause of death among children. Safer firearm storage practices are associated with a reduced risk of childhood suicide and unintentional...
BACKGROUND
Firearm injury is a leading cause of death among children. Safer firearm storage practices are associated with a reduced risk of childhood suicide and unintentional firearm death. However, these practices are underutilized. The objective of this study was to characterize parental attitudes and beliefs related to firearm storage and identify facilitators and barriers to safer storage practices.
METHODS
Semi-structured, qualitative interviews were conducted to identify motivations for using different storage methods among parents who kept firearms in southern Connecticut. The constant comparative method was used to code interview transcripts and derive themes directly from the data.
RESULTS
Twenty participants completed the study. 60% were male, 90% were white, and all were between 32 and 53 years old. 85% of participants stored firearms locked, 60% unloaded, 65% kept ammunition locked or did not keep ammunition in their home, and 45% stored ammunition separate from firearms. The following themes were identified: (1) firearm storage must be compatible with a specific context of use; (2) some parents engage in higher-risk storage because they believe it is adequate to reduce the risk of injury; (3) firearm practices are influenced by one's social network and lived experience; (4) parents who own firearms may be amenable to changing storage practices; and (5) parents' conceptualization of firearm injury prevention is multimodal, involving storage, education, and legislation.
CONCLUSIONS
Parents who keep firearms value convenience and utility, which may be at odds with safer storage practices; however, some may be amenable to adopting safer practices. Family and peer relationships, education, and legislation represent important facilitators of storage practices. Understanding parental attitudes and beliefs on firearm storage may inform future interventions to improve storage practices.
PubMed: 36544237
DOI: 10.1186/s40621-022-00400-x -
Computational and Structural... 2021About fifty times more data has been created than there are stars in the observable universe. Current trends in data creation and consumption mean that the devices and... (Review)
Review
About fifty times more data has been created than there are stars in the observable universe. Current trends in data creation and consumption mean that the devices and storage media we use will require more physical space. Novel data storage media such as DNA are considered a viable alternative. Yet, the introduction of new storage technologies should be accompanied by an evaluation of user requirements. To assess such needs, we designed and conducted a survey to rank different storage properties adapted for visualization. That is, accessibility, capacity, usage, mutability, lifespan, addressability, and typology. Withal, we reported different storage devices over time while ranking them by their properties. Our results indicated a timeline of three distinct periods: magnetic, optical and electronic, and alternative media. Moreover, by investigating user interfaces across different operating systems, we observed a predominant presence of bar charts and tree maps for the usage of a medium and its file directory hierarchy, respectively. Taken together with the results of our survey, this allowed us to create a customized user interface that includes data visualizations that can be toggled for both user groups: Experts and Public.
PubMed: 34527195
DOI: 10.1016/j.csbj.2021.08.031 -
European Annals of Allergy and Clinical... Jul 2018The families of seed storage proteins, together with profilins, oil-bodies-associated oleosins, and pathogenesis-related (PR) proteins like PR-10 (Bet v 1-like), PR-12... (Review)
Review
The families of seed storage proteins, together with profilins, oil-bodies-associated oleosins, and pathogenesis-related (PR) proteins like PR-10 (Bet v 1-like), PR-12 (defensins) and PR-14 (non-specific lipid transfer protein), are the main causes of IgE sensitization to tree nuts, legumes and seeds. All these allergens, with the exclusion of profilins and of PR-10, are heat-stable and possibly responsible for fatal or almost fatal adverse reactions to such foods. In this short review, we will discuss the relationship and amino acid identities among some of the seed storage homologue molecules identified to date from tree nuts, seeds and legumes.
Topics: Allergens; Antigens, Plant; Fabaceae; Humans; Immunoglobulin E; Nut Hypersensitivity; Nuts; Seed Storage Proteins; Seeds; Sequence Homology, Amino Acid
PubMed: 29479929
DOI: 10.23822/EurAnnACI.1764-1489.54