• (iga nephropathy) A chronic autoimmune glomerulonephritis characterized by the deposition of immunoglobulin A in the mesangium of the glomeruli. It is manifested with hematuria and mild proteinuria.
  NCI Thesaurus
  U.S. National Cancer Institute, 2021
• (iga nephropathy) Glomerulonephropathy characterized by mesangial deposition of IgA antibody in the glomerulus. It is often characterized by hematuria, which may include episodes of visible hematuria during acute illness, and/or proteinuria.
  NICHD Pediatric Terminology
  U.S. National Cancer Institute, 2021
• (iga nephropathy) Most common cause of primary glomerular disease in Europe, Australia, and United States; lesions formed as a consequence of mesangial formations of immune deposits composed of IgA.
  CRISP Thesaurus
  National Institutes of Health, 2006
• (glomerulonephritis, iga) A chronic form of glomerulonephritis characterized by deposits of predominantly IMMUNOGLOBULIN A in the mesangial area (GLOMERULAR MESANGIUM). Deposits of COMPLEMENT C3 and IMMUNOGLOBULIN G are also often found. Clinical features may progress from asymptomatic HEMATURIA to END-STAGE KIDNEY DISEASE.
  NLM Medical Subject Headings
  U.S. National Library of Medicine, 2021
• (focal glomerulonephritis) Inflammation of a specific segment of glomeruli within the kidney.
  NCI Thesaurus
  U.S. National Cancer Institute, 2021
• Immunoglobulin A (IgA) nephropathy is deposition of IgA immune complexes in glomeruli, manifesting as slowly progressive hematuria, proteinuria, and, often, renal insufficiency. Diagnosis is based on urinalysis and renal biopsy. Prognosis is generally good. Treatment options include angiotensin-converting enzyme (ACE) inhibitors,...
  Merck Manuals
  Merck & Co., Inc., 2020
• Immunoglobulin A (IgA) nephropathy (also known as Berger disease) was first described by Berger and Hinglais in 1968. IgA nephropathy is characterized by predominant IgA deposition in the glomerular mesangium.
  Medscape
  WebMD, 2019
• IgA nephropathy (nuh-FROP-uh-thee), also known as Berger's disease, is a kidney disease that occurs when an antibody called immunoglobulin A (IgA) builds up in your kidneys. This results in local inflammation that, over time, can hamper your kidneys' ability to filter waste from your blood.
  Mayo Clinic
  Mayo Foundation for Medical Education and Research
• IgA nephropathy is a kidney disorder that occurs when IgA (immunoglobulin A), a protein that helps the body fight infections, settles in the kidneys. IgA nephropathy can occur at any age, even in childhood. After many years, deposits of IgA may cause the kidneys to leak blood and sometimes protein in the urine. In the early stages, IgA...
  NIH Genetic and Rare Diseases
  National Center for Advancing Translational Sciences
• IgA nephropathy (IgAN) is defined by the presence of dominant or co-dominant mesangial IgA immune deposits, often accompanied by C3 and IgG in association with a mesangial proliferative glomerulonephritis of varying severity. The etiology of this common glomerulonephritis remains unknown. Clinical presentation varies widely. Patients...
  Epocrates
  Athenahealth, Inc., 2019