Pharmacologic Substance
atomoxetine hydrochloride
Effect:
Increased Cerebral Cortex Norepinephrine Activity
May Treat:
Attention Deficit Disorder with Hyperactivity
More Information:
Definitions related to atomoxetine hydrochloride:
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A propylamine derivative and selective ADRENERGIC UPTAKE INHIBITOR that is used in the treatment of ATTENTION DEFICIT HYPERACTIVITY DISORDER.NLM Medical Subject HeadingsU.S. National Library of Medicine, 2021
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The hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant, norepinephrine reuptake inhibitor with cognitive-enhancing activity. Although its precise mechanism of action is unknown, atomoxetine appears to selectively inhibit the pre-synaptic norepinephrine transporter, resulting in inhibition of the presynaptic reabsorption of norepinephrine and prolongation of norepinephrine activity in the synaptic cleft. The effect on cognitive brain function may result in improved attention and decreased impulsivity and activity levels.NCI ThesaurusU.S. National Cancer Institute, 2021
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