Pharmacologic Substance
citalopram Audio
[ sahy-tal-uh-pram ]
Brand Names:
Celexa
Effect:
Increased Central Nervous System Serotonin Activity
May Treat:
Alcoholism; Dementia; Depressive Disorder; Diabetic Neuropathies; Obsessive-Compulsive Disorder; Tobacco Use Disorder
More Information:
ChemID; DrugBank; DailyMed; DrugInfo; PDR
Definitions related to citalopram:
  • A bicyclic phthalene derivative and selective serotonin reuptake inhibitor (SSRI), with antidepressant and anxiolytic activities. Citalopram selectively inhibits the neuronal reuptake of the neurotransmitter serotonin (5-HT) in presynaptic cells in the central nervous system, thereby increasing levels of 5-HT within the synaptic cleft and enhancing the actions of serotonin on its receptors. Increased serotonergic neurotransmission results in antidepressive and anxiolytic effects.
    NCI Thesaurus
    U.S. National Cancer Institute, 2021
  • A furancarbonitrile that is one of the serotonin uptake inhibitors used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from TARDIVE DYSKINESIA in preference to tricyclic antidepressants, which aggravate dyskinesia.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2021
  • Selective neuronal serotonin reuptake inhibitor and a clinically effective antidepressant with tolerable side effects; effective in reducing ethanol uptake in alcoholics.
    CRISP Thesaurus
    National Institutes of Health, 2006
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.