Disease or Syndrome
cryoglobulinemia
Subclass of:
Vascular Hemostatic Disorders;
Paraproteinemias
Definitions related to cryoglobulinemia:
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A condition characterized by the presence of cryoglobulins in the blood. Cryoglobulins are abnormal proteins that precipitate within the microvasculature on exposure to cold; microvasculature effects of cryoglobulinemia may result in restricted tissue blood flow, tissue hypoxia, and tissue necrosis. --2004NCI ThesaurusU.S. National Cancer Institute, 2021
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Increased level of cryoglobulins in the blood. Cryoglobulins are abnormal immunoglobulins, especially IGG or IGM, that precipitate spontaneously when serum is cooled below 37 degrees Celsius.Human Phenotype Ontology (HPO)The Human Phenotype Ontology Project, 2021
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Cryoglobulins are single or mixed immunoglobulins that undergo reversible precipitation at low temperatures. Several types of cryoglobulins have been identified, and the potential clinical manifestations vary by cryoglobulin type.WebMD, 2019
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Cryoglobulins are abnormal proteins in the blood. If you have cryoglobulinemia (kry-o-glob-u-lih-NEE-me-uh), these proteins may clump together at temperatures below 98.6 F (37 C). These gelatinous protein clumps can impede your blood circulation, which can damage your skin, joints, nerves and organs - particularly your kidneys and liver.Mayo Foundation for Medical Education and Research
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Cryoglobulinemia refers to the presence of cryoglobulins in the serum. Cryoglobulins are immunoglobulins that reversibly precipitate at temperatures below 98.6�F (below 37�C). Type I cryoglobulinemia is usually associated with lymphoproliferative disorders. Types II and III may be associated with infectious (hepatitis C virus infection)...Athenahealth, Inc., 2019
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Cryoglobulinemia, presence in the blood of proteins called cryoglobulins that precipitate at temperatures below 98.6� F (37� C), both in the laboratory and in the body (where the precipitation could cause circulatory impairment or blockage or sometimes hemorrhage). Cryoglobulinemia is usually...Encyclopedia Britannica, Inc., 2020
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