Disease or Syndrome
renal insufficiency
re·nal in·suf·fi·cien·cy [ reen-l in-suh-fish-uhn-see ]
Subclass of:
Kidney Diseases
Definitions related to renal insufficiency:
  • (renal impairment) An acute or chronic condition where the kidneys are not functioning normally.
    U.S. FDA Glossary
    U.S. Food & Drug Administration, 2021
  • A reduction in the level of performance of the kidneys in areas of function comprising the concentration of urine, removal of wastes, the maintenance of electrolyte balance, homeostasis of blood pressure, and calcium metabolism.
    Human Phenotype Ontology (HPO)
    The Human Phenotype Ontology Project, 2025
  • Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.