Hormone
betamethasone
[ bey-tuh-meth-uh-sohn, bee- ]
Brand Names:
Betagen brand of Betamethasone and Gentamicin; Betavet; Celestone Soluspan; Del-Beta; Diprolene; Enstilar; Genone; Gentacalm; GentaVed; Lotrisone; Luxiq; Malotic; Otomax; Relifor; Sernivo; Taclonex; Tri-Otic for Canines; Vetromax; Wynzora
Effect:
Antipruritic Activity; Carbohydrate Metabolism Alteration; Decreased Cellular Migration; Decreased Glucocorticoid Secretion; Decreased Leukotriene Activity; Decreased Lysosomal Function; Decreased Prostaglandin Activity; Decreased Protein Synthesis; Decreased Thromboxane Activity; Lipid Metabolism Alteration
May Treat:
Dermatitis, Atopic; Dermatitis, Seborrheic; Facial Dermatoses; Foot Dermatoses; Hand Dermatoses; Inflammation; Leg Dermatoses; Pruritus Ani; Psoriasis; Scalp Dermatoses
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to betamethasone:
  • A glucocorticoid given orally, parenterally, by local injection, by inhalation, or applied topically in the management of various disorders in which corticosteroids are indicated. Its lack of mineralocorticoid properties makes betamethasone particularly suitable for treating cerebral edema and congenital adrenal hyperplasia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p724)
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory activities. Betamethasone binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.
    NCI
    U.S. National Cancer Institute, 2021
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