Pharmacologic Substance
prazosin
[ prey-zoh-sin ]
Brand Names:
Minipress
Effect:
Arterial Vasodilation; Decreased Bladder Sphincter Tone; Decreased Blood Pressure; Venous Vasodilation
May Treat:
Hypertension; Prostatic Hyperplasia; Raynaud Disease; Urinary Retention
More Information:
ChemID; DrugBank; DailyMed; PDR
Definitions related to prazosin:
  • 1-(4-amino-6,7-dimethoxy- 2-quinazolinyl) -4-(2-furoyl) piperazine.
    CRISP Thesaurus
    National Institutes of Health, 2006
  • A member of a class of drugs called alpha blockers. Prazosin eases the symptoms of benign prostatic hyperplasia by relaxing smooth muscle tissue in the capsule that surrounds the prostate.
    Harvard Dictionary of Health Terms
    Harvard Medical Publishing, 2011
  • A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
  • A synthetic piperazine derivative and an alpha-1 adrenergic receptor inhibitor used primarily as an anti-hypertensive. Prazosin's effects are most pronounced in the large resistance vessels (i.e. arterioles) and result in a decrease in total systemic vascular resistance (SVR) without a rebound or reflex tachycardia. To a lesser extent, this agent also decreases the tone of the bladder sphincter, thereby allowing the opening of the bladder into the urethra and thus relieving the urinary conditions associated with benign prostatic hypertrophy.
    NCI
    U.S. National Cancer Institute, 2021
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.