Pharmacologic Substance
astemizole
Effect:
Decreased Histamine Activity
May Treat:
Conjunctivitis, Allergic; Rhinitis, Allergic, Perennial; Urticaria
Definitions related to astemizole:
  • A synthetic piperidinyl-benzimidazol derivative with antiallergic properties, Astemizole acts as a reversible competitive inhibitor of histamine H1 receptors, with less anticholinergic effects compared to related agents. It is a long-acting, non-sedative antihistaminic used in the treatment of seasonal allergic rhinitis, asthma, allergic conjunctivitis, and chronic idiopathic urticaria. (NCI04)
    NCI
    U.S. National Cancer Institute, 2021
  • Antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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This content should not be used in place of medically-reviewed decision support reference material or professional medical advice. Some terms may have alternate or updated definitions not reflected in this set. The definitions on this page should not be considered complete or up to date.