Pharmacologic Substance
nocodazole
Subclass of:
Benzimidazoles
Definitions related to nocodazole:
  • A synthetic tubulin-binding agent with antineoplastic activity. Nocodazole binds to beta-tubulin and disrupts microtubule assembly/disassembly dynamics. This prevents mitosis and induces apoptosis in tumor cells. Although nocodazole binding site overlaps with that of colchicine, the two agents are structurally quite different.
    NCI
    U.S. National Cancer Institute, 2021
  • Nocodazole is an antineoplastic agent which exerts its effect by depolymerizing microtubules.
    NLM Medical Subject Headings
    U.S. National Library of Medicine, 2025
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